Detalhe da pesquisa
1.
Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke.
Cell
; 177(5): 1262-1279.e25, 2019 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31056284
2.
Hemin-Induced Death Models Hemorrhagic Stroke and Is a Variant of Classical Neuronal Ferroptosis.
J Neurosci
; 42(10): 2065-2079, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34987108
3.
Temporary induction of hypoxic adaptations by preconditioning fails to enhance Schwann cell transplant survival after spinal cord injury.
Glia
; 71(3): 648-666, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36565279
4.
Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases.
Neurobiol Dis
; 147: 105145, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33127469
5.
The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson's disease.
Neurobiol Dis
; 136: 104725, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31911115
6.
N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice.
Ann Neurol
; 84(6): 854-872, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30294906
7.
Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis.
Stroke
; 48(4): 1033-1043, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250197
8.
Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition.
J Neurosci
; 34(43): 14328-37, 2014 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25339746
9.
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.
J Neurosci Res
; 91(8): 1066-75, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23456821
10.
Sodium salicylate protects against rotenone-induced parkinsonism in rats.
Synapse
; 67(8): 502-14, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23447126
11.
2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience.
Neuron
; 111(18): 2831-2846.e10, 2023 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37453419
12.
A STING agonist preconditions against ischaemic stroke via an adaptive antiviral Type 1 interferon response.
Brain Commun
; 4(3): fcac133, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35694149
13.
Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.
PLoS One
; 16(4): e0249591, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33819286
14.
HIF1α stabilization in hypoxia is not oxidant-initiated.
Elife
; 102021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34596045
15.
Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage.
Sci Immunol
; 6(56)2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891558
16.
New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases.
Front Aging Neurosci
; 13: 623751, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33584250
17.
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.
Neurochem Int
; 54(2): 111-8, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19041676
18.
Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors.
eNeuro
; 6(1)2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30783618
19.
The interferon response as a common final pathway for many preconditioning stimuli: unexpected crosstalk between hypoxic adaptation and antiviral defense.
Cond Med
; 1(4): 143-150, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30198023
20.
Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body ß-hydroxybutyrate.
Elife
; 52016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27253067